During the naturalization process of white pine blister rust (WPBR, caused by Cronartium ribicola), susceptible pine genotypes will be selected against, along with any traits that are associated with those genotypes, potentially causing a shift in the suite of traits in the post-selection population compared to the native population. Consequently, identifying associated traits with WPBR resistance is critical for effective restoration planning, especially in a changing climate. We sought to determine whether complete resistance to WPBR in limber pine (Pinus flexilis) is associated with abiotic stress tolerances, particularly those related to freezing and drought. Previous research has noted that proteins involved in partial resistance to C. ribicola also exhibit antifreeze capabilities in vitro and very likely enhance plant frost tolerance in vivo; these proteins are also expressed in response to cold and, occasionally, drought. It is not known if a similar association exists between the major gene in limber pine (Cr4) and tolerance of abiotic stress.