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    Author(s): Dan Cullen
    Date: 2007
    Source: Nature biotechnology. Vol. 25, no. 2 (Feb. 2007): Pages 189-190
    Publication Series: Miscellaneous Publication
    PDF: View PDF  (123 KB)

    Description

    Few microbes compare with the filamentous fungus Aspergillus niger in its ability to produce prodigious amounts of useful chemicals and enzymes. This fungus is the principal source of citric acid for food, beverages and pharmaceuticals and of several important commercial enzymes, including glucoamylase, which is widely used for the conversion of starch to food syrups and to fermentative feedstocks for ethanol production. Although most of these fermentation processes are well established, the underlying genetics are still poorly understood. In this issue, Pel et al. report the genome sequence of A. niger strain CBS 513.88. The availability of this sequence should provide invaluable aid toward improving the production of chemicals and enzymes in this organism.

    Publication Notes

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    • This article was written and prepared by U.S. Government employees on official time, and is therefore in the public domain.

    Citation

    Cullen, Dan 2007. The genome of an industrial workhorse : sequencing of the filamentous fungus Aspergillus niger offers new opportunities for the production of specialty chemicals and enzymes. Nature biotechnology. Vol. 25, no. 2 (Feb. 2007): Pages 189-190

    Keywords

    Nucleotide sequence, genomes, fungi, industrial applications, enzymes, biotechnology, genetic engineering, Aspergillus niger, genetics, biodegradation, gene expression, microbial metabolism, regulation, fermentation, citric acid, chemical engineering, decay fungi, glucoamylase

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