Skip to Main Content
U.S. Forest Service
Caring for the land and serving people

United States Department of Agriculture

Home > Search > Publication Information

  1. Share via EmailShare on FacebookShare on LinkedInShare on Twitter
    Dislike this pubLike this pub
    Author(s): Jennifer Van Vleet; Thomas W. Jeffries
    Date: 2009
    Source: Current opinion in biotechnology. Vol. 20, no. 3 (June 2009): pages 300-306.
    Publication Series: Miscellaneous Publication
    PDF: Download Publication  (210.51 KB)


    Efficient fermentation of hemicellulosic sugars is critical for the bioconversion of lignocellulosics to ethanol. Efficient sugar uptake through the heterologous expression of yeast and fungal xylose/glucose transporters can improve fermentation if other metabolic steps are not rate limiting. Rectification of cofactor imbalances through heterologous expression of fungal xylose isomerase or modification of cofactor requirements in the yeast oxidoreductase pathway can reduce xylitol production while increasing ethanol yields, but these changes often occur at the expense of xylose utilization rates. Genetic engineering and evolutionary adaptation to increase glycolytic flux coupled with transcriptomic and proteomic studies have identified targets for further modification, as have genomic and metabolic engineering studies in native xylose fermenting yeasts

    Publication Notes

    • We recommend that you also print this page and attach it to the printout of the article, to retain the full citation information.
    • This article was written and prepared by U.S. Government employees on official time, and is therefore in the public domain.


    Van Vleet, Jennifer; Jeffries, Thomas W. 2009. Yeast metabolic engineering for hemicellulosic ethanol production. Current opinion in biotechnology. Vol. 20, no. 3 (June 2009): pages 300-306.


    Google Scholar


    Alcohol, yeast fungi, biotechnology, fungi, industrial applications, genetic engineering, microbial metabolism, genetics, lignocellulose, fermentation, gene expression, genomes, wood-decaying fungi, genetic transcription, Saccharomyces cerevisiae, hemicellulose, sugars, glucose, oxidoreductase, ethanol, decay fungi, xylose, bioconversion

    Related Search

    XML: View XML
Show More
Show Fewer
Jump to Top of Page