Skip to Main Content
Duplications and losses in gene families of rust pathogens highlight putative effectorsAuthor(s): Amanda L. Pendleton; Katherine E. Smith; Nicolas Feau; Francis M. Martin; Igor V. Grigoriev; Richard Hamelin; C.Dana Nelson; J.Gordon Burleigh; John M. Davis
Source: Frontiers in Plant Science, Volume 5 Article 299
Publication Series: Scientific Journal (JRNL)
Station: Southern Research Station
View PDF (1.82 MB)
DescriptionRust fungi are a group of fungal pathogens that cause some of the world’s most destructive diseases of trees and crops . A shared characteristic among rust fungi is obligate biotrophy, the inability to complete a lifecycle without a host. This dependence on a host species likely affects patterns of gene expansion, contraction, and innovation within rust pathogen genomes. The establishment of disease by biotrophic pathogens is reliant upon effector proteins that are encoded in the fungal genome and secreted from the pathogen into the host’s cell apoplast or within the cells. This study uses acomparative genomic approach to elucidate putative effectors and determine their evolutionary histories. We used OrthoMCL to identify nearly 20,000 gene families in proteomes of 16 diverse funga species, which include 15 basidiomycetes and one ascomycete. We inferred patterns o fduplication and loss for each gene family and identified families with distinctive patterns of expansion/contraction associated with the evolution of rust fungal genomes. To recognize potential contributors for the unique eatures of rust pathogens,we identified families harboring secreted proteins that (i) arose or expanded in rust pathogens relative to other fungi, or (ii) contracted or were lost in rust fungal genomes. While the origin of rust fungi appears to be associated with considerable gene loss, there are many gene duplications associated with each sampled rust funga lgenome. We also highlight two putative effector gene families that have expanded in Cqf that we hypothesize have roles in pathogenicity.
- You may send email to email@example.com to request a hard copy of this publication.
- (Please specify exactly which publication you are requesting and your mailing address.)
- We recommend that you also print this page and attach it to the printout of the article, to retain the full citation information.
- This article was written and prepared by U.S. Government employees on official time, and is therefore in the public domain.
CitationPendleton, Amanda L.; Smith, Katherine E.; Feau, Nicolas; Martin, Francis M.; Grigoriev,Igor V.; Hamelin,Richard;Nelson, C.Dana; Burleigh,J.Gordon; Davis, John M. 2014. Duplications and losses in gene families of rust pathogens highlight putative effectors. Frontiers in Plant Science, Volume 5 Article 299. 13 p.
Keywordseffectors, rustpathogens, secretome, genomeevolution, comparativegenomics
- Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78
- Global and comparative protein profiles of the pronotum of the southern pine beetle, Dendroctonus frontalis
- Gene expression patterns of wood decay fungi Postia placenta and Phanerochaete chrysosporium are influenced by wood substrate composition during degradation
XML: View XML