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Synthesis, X-ray structure, and hydrolytic chemistry of the high potent antiviral polyniobotungstate A-[alpha]-[Si2Nb6W18O77]8–Author(s): Gyu-Shik Kim; Huadong Zeng; Jeffrey T. Rhule; Ira A. Weinstock; Craig L. Hill
Source: Chemical communication. (1999): Pages 1651-1652
Publication Series: Miscellaneous Publication
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DescriptionPotently antiviral polyniobotungstates have been structurally characterized; the dimer A-[alpha]-[Si2Nb6W18O77]8– cleaves cleanly to the monomer A-[alpha]-[SiNb3W9O40]7– within 1 min in aqueous solution buffered at physiological (neutral) pH establishing that the monomer and not the dimer is pharmacologically relevant.
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CitationKim, Gyu-Shik; Zeng, Huadong; Rhule, Jeffrey T.; Weinstock, Ira A.; Hill, Craig L. 1999. Synthesis, X-ray structure, and hydrolytic chemistry of the high potent antiviral polyniobotungstate A-[alpha]-[Si2Nb6W18O77]8–. Chemical communication. (1999): Pages 1651-1652
KeywordsPolyniobotungstate, synthesis, X-ray structure, hydrolytic chemistry, antiviral properties
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